2011 – In a most memorable first career MLB start at first base, Carlos Santana begins a triple play in the fourth inning of a 7-1 Indians win over the Chicago White Sox in front of a then-record low crowd of 8,726 fans at Progressive Field.

With the Indians down 1-0 in the top of the fourth, Cleveland starter Justin Masterson walked the leadoff batter, Carlos Quentin, and gave up a hit to A.J. Pierzynski. Chicago shortstop Alexei Ramirez attempted to drop down a bunt but popped it up. Santana, charging in on the play, made a diving catch on the foul line half way down the line, threw to second baseman Orlando Cabrera covering at first to eliminate Pierzynski, and Cabrera threw to shortstop Asdrubal Cabrera at second to force Quentin to end the inning.

The Indians would take the lead in the sixth on a two-run homer and score seven unanswered runs to win their first game of the season and to avoid a first series sweep at the hands of the Sox.

The triple play was the 32nd in club history, including the only postseason variety in 1920 and three different unassisted ones.